Is Acyclovir Safe To Take Long-Term?

Is acyclovir hard on the kidneys?

Acute kidney injury is an unfortunate complication of acyclovir therapy secondary to crystal-induced nephropathy.

It is characterized by a decrease in renal function that develops within 24–48 hours of acyclovir administration indicated by a rapid rise in the serum creatinine..

What should you not take with acyclovir?

Common medications that may interact with acyclovir include:amphotericin.clozapine.hepatitis B medications, such as entecavir.HIV medications, such as tenofovir and zidovudine.gentamicin.NSAIDs, such as ibuprofen, diclofenac, or naproxen.other antivirals, such as valacyclovir.probenecid.More items…•Jan 27, 2020

What viruses does acyclovir treat?

Acyclovir injection is used to treat severe infections caused by herpes viruses, including severe forms of genital herpes, shingles, herpes encephalitis (swelling of the brain), and herpes infections in people with other diseases that weaken the immune system.

Can I take acyclovir as a preventative?

Three antiviral drugs are approved to treat or suppress outbreaks of genital herpes: acyclovir, famciclovir and valacyclovir. Most clinically apparent outbreaks can be prevented by taking one of these drugs daily. In addition, daily acyclovir reduces asymptomatic viral shedding by 95%.

Can you become resistant to acyclovir?

Acyclovir resistance is not common but does occur at higher rates in immunocompromised patients. Acyclovir resistance can be attributed to thymidine kinase mutations and confers cross-resistance among the antiviral nucleoside analogs (acyclovir, valacyclovir, famciclovir, and penciclovir).

Can acyclovir cause eye problems?

Ophthalmic acyclovir may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: eye stinging. red, swollen, or itchy eyelids.

Can you take acyclovir long term?

Nevertheless, we conclude that the use of oral acyclovir for more than 12 months provides substantial additional prevention against recurrence of ocular HSV. Our data suggest that long-term oral acyclovir use remains effective in decreasing the number of recurrences beyond 12 months.

Is acyclovir safe to take everyday?

The tablets, capsules, and suspension are usually taken with or without food two to five times a day for 5 to 10 days, starting as soon as possible after your symptoms begin. When acyclovir is used to prevent outbreaks of genital herpes, it is usually taken two to five times a day for up to 12 months.

Does acyclovir speed up healing?

It can speed up healing of the sores and decrease symptoms (such as tingling, pain, burning, itching). Acyclovir belongs to a class of medications known as antivirals. It works by stopping the growth of the virus.

Can you drink alcohol while taking acyclovir?

Alcohol will not interfere with the way the antiviral drugs works. Acyclovir will still be effective.

Do antivirals weaken immune system?

Whereas AZT, ribavirin, or ganciclovir were antiproliferative, ddI or acyclovir had little, if any, effect on PBMC mitogenesis. The inhibitory effects of antivirals on immune cells may contribute to the immune deterioration observed in patients following prolonged use of the drugs.

What do you do if acyclovir doesn’t work?

If the response is poor, the dose of oral ACV should be increased to 800 mg five times a day. If no response seen after 5 to 7 days, it is unlikely that the lesion will respond to intravenous ACV (or chemically and structurally related drugs such as VCV or famciclovir), so an alternative regimen must be assigned.

How many years can you take acyclovir?

Long-term use of acyclovir for up to 10 years for HSV suppression is effective and well tolerated. Acyclovir is also approved for use in children, is available in some countries over the counter in cream formulation for herpes labialis, and has been monitored in over 1000 pregnancies.

What are the long term side effects of acyclovir?

Serious side effectsUnusual changes in your mood or behavior. Symptoms can include: … Decrease in your red blood cells and platelets. Symptoms can include: … Liver problems.Muscle pain.Skin reactions. Symptoms can include: … Changes in your vision.Kidney failure. Symptoms can include: … Allergic reaction. Symptoms can include:

Which is better Valtrex or acyclovir?

Valacyclovir (Valtrex) and acyclovir (Zovirax) are antiviral drugs that work by interfering with viral DNA replication. Both drugs target the same viruses but valacyclovir provides longer duration of action, therefore, doses can be taken fewer times every day – this is the only real advantage.

How much water should you drink when taking acyclovir?

Acyclovir capsules, tablets, and oral suspension may be taken with meals or on an empty stomach. Acyclovir is best taken with a full glass (8 ounces) of water.

Is acyclovir making my hair fall out?

Acyclovir is an antiviral drug used to slow the growth and spread of the herpes virus. Treatment with oral acyclovir can lead to hair loss (1). “Drug-induced alopecia (hair loss) usually occurs as a diffuse noncicatricial alopecia (a non-scarring hair loss) that recovers after discontinuation of the drug.

How common are acyclovir side effects?

Acyclovir has a few common, minor side effects, as well as less common and rare side effects. These can be more serious….The following side effects of acyclovir are rare :abdominal pain.dizziness and fatigue.hair loss.allergic reactions.anemia.anorexia.mood changes, such as aggression or agitation.confusion.More items…

What happens when I stop taking acyclovir?

If you stop taking acyclovir too soon or skip doses, your infection may not be completely treated or may become more difficult to treat.

Is acyclovir hard on your liver?

This is similar in other antiviral drugs used to treat herpes, such as acyclovir, which has “little evidence” of causing significant liver injury, according to the National Institutes of Health. For healthy people with normal liver function, antiviral herpes medications are not harmful.

How much Acyclovir is too much?

Aciclovir 800 mg Tablets are not usually harmful, unless you take too much over several days. Talk to your doctor or pharmacist if you take too much Aciclovir 800 mg Tablets. Take the medicine pack with you. it is nearly time for your next dose, skip the missed dose.